6.1. Known Benefits
The known benefits among recipients of the proposed vaccine relative to placebo are:
• Reduction in the risk of confirmed COVID-19 occurring at least 7 days after Dose 2
• Reduction in the risk of confirmed COVID-19 after Dose 1 and before Dose 2
• Reduction in the risk of confirmed severe COVID-19 any time after Dose 1
The protocol-specified 2-dose vaccination regimen was highly effective in preventing PCRconfirmed COVID-19 occurring at least 7 days after completion of the vaccination regimen.
Additional primary efficacy analyses in the all-available efficacy population, including
participants who had protocol violations, showed consistency with outcomes in the primary
analysis population. Efficacy findings were also consistent across various subgroups, including
racial and ethnic minorities, participants aged 65 years and older, and those with one or more of
the following conditions: obesity, diabetes, hypertension, and chronic cardiopulmonary
diseases.
Among participants with no evidence of COVID-19 prior to vaccination, the vaccine was
effective in reducing the risk of COVID-19 and severe COVID-19 after Dose 1. Fewer severe
cases were also observed in the vaccine recipients relative to recipients of placebo during the
follow up period after Dose 1. The findings post Dose 1, from a post-hoc analysis, cannot be the
basis to assess the potential efficacy of the vaccine when administered as a single dose
because the period of observation is limited by the fact that most participants received a second
dose three weeks after the first one.
Lo que reduce el riesgo de tener sintomas graves es la Dosis 1, pero al 2a ya te inmuniza a tener el virus per se...
En serio, me hace gracia la gente que dice que no se sabe nada blablablabla pero no se han leido las cientos de páginas que hay de estudios al respecto.